Mysimba | Weight Loss Tablets
Doctor itemA free online consultation is required before this treatment can be supplied.
What is Mysimba?
These tablets are available in the UK and you can order Mysimba online through services like UK-registered Ashcroft Pharmacy.
Mysimba (POM) is a weight-loss tablet for adults with obesity (BMI over 30) or overweight (BMI 27-30) with weight-related health conditions like diabetes, high blood pressure or high cholesterol.
It combines two drugs, naltrexone and bupropion, to help reduce appetite and support weight loss when used with a doctor-recommended healthy diet and exercise plan.
BMI Definition: BMI is a measure of body weight in relation to height. Obesity in adults is defined as a BMI of 30 or higher. Overweight is defined as a BMI between 27 and less than 30.
What is Mysimba tablets used for?
Mysimba (prescription weight loss treatment) is used by overweight or obese adults, in conjunction with a reduced-calorie diet and increased physical activity, to support weight loss.
Approval for Use:
Mysimba is approved for use in patients with a BMI of 30 or higher. It can also be prescribed for those with a BMI between 27 and less than 30 if they have additional weight-related conditions such as high blood pressure (hypertension), type 2 diabetes, or high lipid (fat) levels in the blood.
Overweight & Obesity
To be considered overweight, an adult needs a BMI of at least 27kg/m2. For obesity, it's a BMI of at least 30kg/m2. Those with a BMI under 30kg/m2 may be eligible for the drug if they are at risk of weight-related problems.
If, after 16 weeks, the patient hasn't lost at least 5 percent of their starting weight, the doctor might stop giving them Mysimba.
Additionally, the doctor could recommend stopping Mysimba treatment if they are concerned about the patient's blood pressure increasing or other safety issues.
How does Mysimba work?
Struggling with constant cravings and feeling sluggish? Mysimba might be the solution that effective. Mysimba works differently from laxatives and stimulants. It doesn't directly affect your intestines' movements. Instead, it works on your brain.
It helps you by using two ingredients: naltrexone and bupropion. These ingredients work on your brain in two ways:
- Naltrexone (opiate antagonists) reduces your desire for food ( less interested in food)
- Bupropion (antidepressants) makes you feel fuller or more satisfied and boosts calorie burning
Together, they help reduce hunger and cravings, allowing you to eat smaller meals and avoid snacking on foods that could lead to weight gain. This makes it easier to stick to a healthy diet and lose weight.
About naltrexone and bupropion
Both naltrexone and bupropion have been used for over 30 years to treat other conditions, like quitting smoking, by controlling cravings.
Mysimba alternatives for weight loss
While Mysimba is a popular weight loss medication, it's not the only option out there. There are several alternatives to consider, such as:
- Saxenda (injectable medicine)
- Wegovy (semaglutide injection pen)
- Orlistat (Branded weight loss hard capsules)
- Xenical (generic version of Orlistat)
- Ozempic (A semaglutide weight loss injection for Type 2 Diabetes)
- Phentermine (an appetite suppressant)
These treatments differ in their active ingredients and how they work, making it essential to explore your options and consult with a healthcare professional to find the best fit for you.
Medically reviewed by:
| Name | Mr Suhail Jamil |
| Role | Superintendent Pharmacist |
Gphc Number |
2069518 |
Frequently asked questions
Mysimba is suitable for adults who are overweight or obese.
To get the full benefits of Mysimba, it may be necessary to take it for at least 16 weeks. Never stop taking Mysimba without first discussing it with your prescriber.
Mysimba comes in tablet form.
Mysimba has some health risks and side effects, like most medications. However, it's safe if a medically trained health care clinician approves its use.
Before starting Mysimba, your doctor should check your blood pressure and pulse, and theyit should be monitored regularly during treatment (weekly checks), especially if you have high blood pressure already. If your blood pressure or pulse stays high, you should stop taking Mysimba.
Mysimba has shown effectiveness in reducing body weight in clinical trials. These studies involved around 4500 obese or overweight patients who received either Mysimba or a placebo alongside counseling and advice on diet and exercise.
In three of the studies, patients on Mysimba lost around 3.7 to 5.7% of their body weight, compared to 1.3 to 1.9% with placebo.
Additionally, a higher proportion of Mysimba-treated patients achieved significant weight loss, with 28 to 42% achieving a 5% weight loss compared to 12 to 14% with placebo.
Furthermore, 13 to 22% of those taking Mysimba achieved at least a 10% reduction in weight, while only 5 to 6% of placebo-treated patients did so.
In another research with more intensive counseling, the weight loss was greater overall: 8.1% with Mysimba compared to 4.9% with placebo.
Here, 46% and 30% of Mysimba-treated patients achieved 5% and 10% weight reductions respectively, compared to 34% and 17% respectively with placebo.
Overall, the effectiveness of Mysimba over placebo was consistent across different methods of analysis, with greater benefits observed in patients who completed 56 weeks of treatment or who had already lost at least 5% of their original body weight by 4 months into the study. Sources
Mysimba comes in prolonged-release tablets containing 7.2 mg naltrexone and 78 mg bupropion, available only with a prescription. The "prolonged-release" feature means the medication releases slowly over several hours.
When you first start Mysimba, a single pack of 112 tablets lasts 5 weeks. Your medicine should be taken as suggested by your prescriber.
When you take Mysimba, you will gradually increase your dose over a four-week period until you reach what is called the maintenance dose. This is the dose at which you will continue to take Mysimba.
Mysimba typically starts showing changes around week eight, based on guidance from the drug company. Studies involving over 4,500 overweight or obese patients indicate that when paired with a reduced-calorie diet and exercise.
Mysimba tablets can significantly impact weight by week 16. If you haven't lost at least 5% of your body weight by then, your prescriber might stop your prescription.
But don't worry, if Mysimba isn't effective for you, we offer other weight loss treatments here at Ashcroft Pharmacy UK.
The exact cost of Mysimba in the UK can vary depending on several factors, including:
Dosage: The number of tablets prescribed per day will affect the total cost.
Pharmacy: Different pharmacies may offer slightly different prices.
Prescription type: There might be a difference between private prescriptions and those provided by the National Health Service (NHS).
At Ashcroft Pharmacy, Mysimba costs around £109 for a starter pack, providing a 1 month supply of 112 tablets at £0.97 per tablet.
You can order Mysimba weight loss pills online through our UK licensed online pharmacy, Ashcroft Pharmacy. Simply complete a quick online assessment form to ensure your suitability for Mysimba. Once approved, our pharmacy team will dispatch your medication to your provided address.
No, Mysimba is not available over the counter. You need a prescription from a doctor to buy it. However, you can purchase it online from Ashcroft Pharmacy uk after a quick online assessment.
The maximum recommended daily dose of Mysimba is two tablets taken twice a day.
Your prescriber will evaluate whether you should continue taking Mysimba after 16 weeks and each year thereafter.
Individuals with liver or kidney problems, or those older than 65, should be cautious. Their doctor may adjust the dose or monitor them more closely.
Swallow your Mysimba tablets whole with food. Do not cut, chew, or crush them.
If you take too many tablets, contact your doctor or nearest hospital emergency department immediately to avoid potential side effects, including seizures.
If you miss a dose, skip it and take the next dose at the usual time. Do not take a double dose to compensate for the missed one.
It may take at least 16 weeks of consistent use to experience the full effects of Mysimba.
The active ingredients in Mysimba are naltrexone and bupropion.
If you miss a dose, skip it and take the next dose at the usual time. Do not take a double dose to compensate for the missed one.