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TTrimethoprim

Trimethoprim

Doctor item
From £9.99

A free online consultation is required before this treatment can be supplied.

What is Trimethoprim?

Trimethoprim 200mg is a prescription only antibiotic that offers effective relief from bacterial infections, particularly urinary tract infections in women, men, children, and older people. Whether you are dealing with an uncomfortable UTI or want protection against recurring infections, Trimethoprim halts bacteria growth and lets your immune system clear the infection. 


Trimethoprim belongs to a drug class called antifolate antibiotics and treats and prevents urinary tract infections, including cystitis. This bacterial infection treatment is suitable for adults and children aged 6 years or older. It is available in the form of:

  • Trimethoprim 200mg tablets

Frequently asked questions

Is Trimethoprim a strong antibiotic?

Trimethoprim is a moderately strong antibiotic against UTIs and some respiratory infections. It inhibits bacterial growth, but its effectiveness depends on bacterial resistance, which has increased in some regions.

What bacteria are killed by Trimethoprim?

Trimethoprim kills Escherichia coli (E.coli) which is the common cause of urinary tract infections. It is also effective against Gram-positive and Gram-negative bacteria such as Enterobacter, Klebsiella, Staphylococcus saprophyticus, and Proteus species. However, resistance to Trimethoprim has increased in some regions.

Is Trimethoprim bad for the kidneys?

Trimethoprim causes kidney problems, especially in people with pre-existing kidney disease. It increases the levels of potassium and creatinine, leading to severe complications. If you have kidney issues, consult your doctor before taking it. 

Are trimethoprim and amoxicillin the same?

Trimethoprim and amoxicillin are not the same. Trimethoprim inhibits the synthesis of bacterial folic acid, while Amoxicillin is a beta-lactam antibiotic that disrupts bacterial cell walls. Trimethoprim is used for UTIs, while Amoxicillin treats dental abscesses, ear, skin, and respiratory infections. Consult your doctor to determine the right fit for you.

Why take Trimethoprim at night?

Trimethoprim is often taken at night or bedtime to enhance its effectiveness as urine production slows down during sleep, letting this antibiotic stay in the bladder longer and work better against infections. It also reduces the risk of possible side effects such as nausea. 

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Written and reviewed by our qualified team — Mr Suhail Jamil, Superintendent Pharmacist (GPhC 2069518).