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GLP-1 Side Effect

GLP-1 medications like Wegovy and Mounjaro may cause side effects such as nausea, vomiting, diarrhea, constipation, bloating, and dry mouth. Most are short-lived, but some may persist and require medical advice. At Ashcroft Pharmacy, you’ll find a range of treatments to help manage these side effects, whether they come from GLP-1 medications or other causes.

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GLP-1 Side Effect medications

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Overview

New weight management treatments, such as Wegovy (semaglutide) and Mounjaro (tirzepatide), can be highly effective; however, some people may experience side effects during the early stages or adjustment phase. 

This page provides practical advice and guidance on managing GLP-1 side effects, including helpful tips and supportive medications. At Ashcroft Pharmacy, we offer expert solutions to help you stay comfortable and on track with your weight management plan.

Most are mild and temporary, but some may need medical attention. Including:

Common Side Effects:

  • Nausea and vomiting usually improve over time.
  • Diarrhoea or constipation – can occur as your body adjusts.
  • Stomach pain or bloating – mild cramping is common.
  • Headaches or fatigue may appear in the first few weeks.

Less Common:

  • Low blood sugar (hypoglycaemia) – mainly if you take other diabetes medicines.
  • Injection site reactions – redness or irritation at the injection site.
  • Pancreatitis or gallbladder issues – rare, but seek medical attention if severe abdominal pain occurs.

How to Reduce Side Effects:

  • Take the medication exactly as prescribed.
  • Stay hydrated and move gently to ease digestion.
  • Eat small, low-fat meals.
  • Report persistent or severe symptoms to your doctor.

Learn more

FAQ

  • What are some common Mounjaro & Wegovy side effects?

    Common side effects from GLP-1 medications like Mounjaro and Wegovy are mild nausea, bloating, constipation, diarrhoea and acid reflux.

  • What products can help with GLP-1 side effects?

    We offer gentle, targeted medications to ease the most common side effects, such as peppermint oil for digestive discomfort, sprays and gels for dry mouth, and Pepto-Bismol for nausea and sickness.

  • Can I take these treatments alongside my weight loss medication?

    Yes, most can be used safely at the same time as your GLP-1 treatment, but always check product guidance and speak to a pharmacist if you’re unsure.

  • When should I speak to a clinician?

    If your symptoms are severe, persistent, or getting worse despite treatment, it’s best to seek medical advice from your GP.

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